I M.PHARM – II Sem
PRINCIPLES OF DRUG DISCOVERY (MPL 203T)
After a successful completion of the course the students will be able to
| Course outcome number | Course Outcomes | Cognitive level |
| CO1 | Remember and list the essential stages in drug discovery, including target identification, lead optimization, and the use of genomics, proteomics, and bioinformatics. | C1 |
| CO2 | Explain how genomics, proteomics, bioinformatics, nucleic acid microarrays, protein microarrays, antisense technologies, siRNAs, antisense oligonucleotides, and transgenic animals are used in target discovery and validation. | C2 |
| CO3 | Execute their understanding of combinatorial chemistry, high throughput screening, in-silico lead discovery techniques, assay development, and protein structure prediction to the lead identification process. | C3 |
| CO4 | Categorize the differences between traditional and rational drug design, explore methods like structure and pharmacophore-based approaches, and assess the various techniques used in virtual screening and docking. | C4 |
| CO5 | Evaluate the historical development of QSAR, compare SAR and QSAR, and assess the relevance and practical applications of QSAR statistical methods and 3D-QSAR approaches. | C5 |
| CO6 | Develop knowledge by creating prodrug designs that address issues like drug solubility, absorption, distribution, site-specific drug delivery, and sustained drug action, considering the rationale and practical considerations of prodrug design. | C6 |
Remembering (C1), Understanding (C2), Applying (C3), Analyzing (C4), Evaluating (C5) and Creating (C6)
