I M.PHARM – II Sem
PHARMACOLOGICAL AND TOXICOLOGICAL SCREENING METHODS – II
(MPL 202T)
After a successful completion of the course the students will be able to
| Course outcome number | Course Outcomes | Cognitive level |
| CO1 | Outline and define key concepts in toxicology, such as acute and chronic studies, reproductive toxicology, genotoxicity, carcinogenicity, safety pharmacology, and regulatory guidelines like OECD, ICH, EPA, and Schedule Y. | C1 |
| CO2 | Discuss the significance of GLP in conducting toxicity studies and comprehend the principles and importance of safety pharmacology, including tiered assessments of cardiovascular, central nervous system, and respiratory safety. | C2 |
| CO3 | Compute their knowledge to design and conduct various types of toxicity studies, such as acute, sub-acute, chronic, dermal, inhalational, reproductive, genotoxicity, and carcinogenicity studies and apply test item characterization methods to regulatory toxicology studies. | C3 |
| CO4 | Distinguish the principles and applications of toxicokinetics in preclinical studies, considering factors like saturation kinetics and evaluating the importance and potential of alternative methods to animal toxicity testing. | C4 |
| CO5 | Assess the importance of IND enabling studies in drug development, including the industry perspective, and assess the list of studies needed for IND submission, considering their role in ensuring drug safety. | C5 |
| CO6 | Develop to synthesize knowledge by creating comprehensive safety assessment plans for drug development, considering toxicological study design, safety pharmacology, and alternative testing methods, while complying with regulatory guidelines. | C6 |
Remembering (C1), Understanding (C2), Applying (C3), Analyzing (C4), Evaluating (C5) and Creating (C6)
